If scaling this recipe up or down, in general, it takes about 1½ hours per pound of meat at 225°F or 30-40 minutes per pound at 250°F.
I prefer to smoke my brisket fat side down.
In terms of wood chips, I recommend hickory, mesquite, oak, maple, or cherry. You could also do a blend of a few kinds.
There is no need to wrap this brisket!
Be sure to let the brisket rest before slicing to lock in the juices.