Preheat the oven to 400°F (200°C). Line a large jelly roll pan with aluminum foil leaving about 2 inches of overhang on the long sides; lightly spray the foil with nonstick spray.
Place the salmon skin-side down in the center of the foil on the prepared pan.
In a small bowl, whisk together the butter, honey, 2 tablespoons lime juice, lime zest, salt, chili powder, cumin, garlic powder, smoked paprika, onion powder, dried oregano, black pepper, and chipotle chili powder to make the wet rub.
Brush or pour the rub evenly over the top of the salmon and rub it gently to coat.
Fold the long sides of the foil up snugly around the salmon without sealing the top; let the salmon rest 15–30 minutes at room temperature while you prepare the mango salsa if needed.
Bake the salmon uncovered at 400°F for about 12–15 minutes, depending on thickness, until the salmon is nearly cooked through.
Switch the oven to broil and broil the salmon for 2–3 minutes to finish and lightly brown the top; watch closely to avoid burning.
Remove the salmon from the oven, spoon mango salsa over the top, garnish with fresh lime juice and chopped cilantro, and season with additional salt to taste.