Preheat your oven to 400°F (200°C). This temperature is perfect for cooking the salmon evenly while allowing the glaze to caramelize slightly.
Line a baking sheet with parchment paper or aluminum foil for easy cleanup. This will also prevent the salmon from sticking.
Place the fresh salmon fillets on the prepared baking sheet. Sprinkle the salt, sugar, ground black pepper, garlic powder, and paprika evenly over the fillets.
In a mixing bowl, combine the mayonnaise with any additional seasonings you prefer. The mayonnaise acts as a base for the tangy glaze, creating a creamy topping that locks in moisture.
Using a spatula, generously spread the mayonnaise mixture over the top of the salmon fillets. Ensure that each piece is well-coated for maximum flavor.
Arrange the lemon slices on top of the glazed salmon. The lemon not only adds flavor but also infuses the fish with a refreshing citrus aroma as it bakes.
Place the baking sheet in the preheated oven and bake for 12-15 minutes, or until the salmon is cooked through and flakes easily with a fork.
Once the salmon is done, remove it from the oven and let it rest for a few minutes. Serve hot, garnished with fresh herbs or additional lemon wedges if desired.