Start by preheating your oven to 350°F (175°C). Line a baking sheet with parchment paper or lightly grease a loaf pan to prevent sticking.
In a small bowl, combine the Italian breadcrumbs and milk. Let them soak for about 5 minutes until the breadcrumbs absorb the milk and become soft. This step ensures your meatloaf stays moist and tender.
In a large mixing bowl, add the ground beef, soaked breadcrumbs, eggs, finely chopped onion, minced garlic, Worcestershire sauce, ketchup, chopped parsley (if using), salt, and black pepper. Use your hands or a spoon to gently mix everything together until just combined. Be careful not to overwork the meat, as that can make the meatloaf tough.
Transfer the meat mixture onto your prepared baking sheet or loaf pan. Shape it into a loaf shape, roughly 9 inches long and 5 inches wide. Make sure it’s evenly packed but not compressed too tightly.
In a small bowl, combine 1/4 cup ketchup, 1 tablespoon brown sugar, and 1 teaspoon Dijon mustard (optional but adds a nice tang). Mix well until smooth.
Spread the glaze evenly over the top of the meatloaf using a spoon or spatula. This glaze will caramelize during baking, creating that signature sticky, flavorful crust.
Place the meatloaf in the preheated oven and bake for 60-70 minutes or until the internal temperature reaches 160°F (70°C). About halfway through baking, you can baste the meatloaf with any glaze that has dripped off to build up a thicker topping.
Once baked, let the meatloaf rest for 10 minutes before slicing. This helps the juices redistribute and keeps your slices firm and juicy.