In a bowl, whisk together the soy sauce, lemon juice, olive oil, Worcestershire sauce, minced garlic, Italian seasoning, black pepper, salt, and a pinch of crushed red pepper until combined.
Place the skirt steak in a resealable plastic bag or shallow dish and pour the marinade over it, making sure the steak is well coated.
Remove excess air from the bag and seal, then refrigerate and marinate for 2 hours (or overnight for more flavor).
Preheat the grill to high heat and oil the grates lightly.
Remove the steak from the marinade and let any excess drip off; discard the marinade.
Grill the skirt steak 3–5 minutes per side, or until an instant-read thermometer inserted into the thickest part reads 145°F for medium doneness.
Transfer the steak to a cutting board and let it rest for 5–10 minutes before slicing against the grain to serve.