Begin by bringing a large pot of salted water to a boil. Once boiling, add the penne pasta and cook according to package instructions until al dente. Reserve about 1 cup of pasta water, then drain the rest and set the pasta aside.
In a large skillet over medium heat, melt the butter. Add the minced garlic and sauté for about 1-2 minutes until fragrant. Be careful not to let it brown, as burnt garlic can impart a bitter taste.
Add the Italian seasoning to the skillet and stir for a few seconds to release its flavor. Then, pour in the crushed tomatoes and stir to combine. Allow this mixture to simmer for 5 minutes, letting the flavors meld together.
Stir in the heavy cream, followed by the Romano cheese, salt, pepper, and garlic powder. Continue to cook for another 3-4 minutes, stirring frequently until the cheese has melted and the sauce is creamy and smooth.
Add the cooked penne pasta to the sauce, tossing gently to coat the pasta evenly. If the sauce seems too thick, add a little reserved pasta water to achieve your desired consistency.
Remove the skillet from heat and fold in the chopped fresh basil. This will add a burst of freshness to the dish, making it even more delightful.
Transfer the Creamy Tomato and Basil Pasta to serving plates. You can garnish with additional grated Romano cheese and basil if desired. Enjoy your meal with a side salad or garlic bread for a complete dining experience!