Preheat the oven to 400°F (200°C). Spray a large baking dish with nonstick spray.
In a large bowl combine ground beef, beaten egg, 1 tablespoon olive oil, grated Romano, panko, minced garlic, dried basil, dried parsley, salt, and pepper; mix gently until just combined.
Use a teaspoon to portion the mixture and roll into small meatballs about the diameter of a nickel; place them in the prepared baking dish in a single layer.
Bake the meatballs for 20 minutes, until cooked through.
While meatballs bake, bring a large pot of salted water to a boil and cook the whole wheat pasta shells until al dente according to package directions; reserve 1/3 cup of the pasta cooking water, then drain.
Heat 1 tablespoon olive oil in a large skillet over medium heat, add the 2 minced garlic cloves and cook briefly until fragrant, about 30 seconds.
Add the canned diced tomatoes, chopped fresh basil, and halved/quartered grape tomatoes to the skillet and stir to combine; add the reserved 1/3 cup pasta water to loosen the sauce.
Add the drained pasta to the skillet and toss to coat in the tomato mixture.
Stir the baked mini meatballs into the skillet with the pasta, turn off the heat, and fold in the ciliegine (mini mozzarella) so they soften in the residual heat.
Serve topped with freshly grated Parmesan and additional chopped basil.