Preheat your air fryer to 360°F.
Halve the 4 avocados lengthwise, remove the pits, scoop the flesh out of the skins, and cut each half into wedges.
Prepare three shallow dishes: put 1/2 cup flour in the first, beat the 3 eggs in the second, and combine 1 cup panko, 1 Tablespoon Italian Seasoning, 1 teaspoon garlic powder, and 1 teaspoon salt in the third.
Working one wedge at a time, dredge each wedge in the flour and shake off excess.
Dip the floured wedge into the beaten eggs, then press it into the panko mixture until evenly coated. Place coated wedges on a plate or tray. Repeat until all wedges are coated (you may need to work in batches).
Arrange the coated avocado wedges in a single layer in the air fryer basket, leaving space between pieces so air can circulate. Cook any remaining wedges in additional batches as needed.
Air fry at 360°F for 5–7 minutes. Carefully flip each wedge and air fry an additional 5–7 minutes, or until the panko is golden and crispy.
Remove the avocado fries from the air fryer and let them rest 1–2 minutes before serving.